CUROSURF administration facilitates transition from
mechanical ventilation (MV)
The table below details the studies in which CUROSURF was used in conjunction with less invasive ventilation. In each study, the addition of CUROSURF to NCPAP helped a majority of infants stay on less invasive ventilation avoiding the need for reintubation or subsequent MV.1-4
The Verder 1994 study at the top of the table compares the success rates of infants receiving CUROSURF + NCPAP vs NCPAP alone. Patients who received CUROSURF in conjunction with NCPAP experienced significantly higher success rates vs NCPAP alone.1
In later studies examining the timing of surfactant administration, a greater number of patients achieved success when CUROSURF was administered early vs late.2,3
About the INSURE method: INtubate → SURfactant → Extubate
The INSURE method of stabilizing infants with RDS involves early surfactant administration followed by rapid extubation to NCPAP. In two recent studies of CUROSURF using the INSURE method, at least 81% of infants were able to successfully avoid subsequent MV and reintubation.3,4
Also take a look at how CUROSURF demonstrates a rapid onset of action and sustained results with fewer doses for fast RDS success.
Interested in evaluating CUROSURF? Find out how you can smoothly integrate CUROSURF into your NICU by participating in the
CUROSURF Experience Program.
Clinical studies have not established that fewer doses, lower volume, or longer dosing intervals result in superior safety or efficacy based on clinically relevant end points.